Turning Medical Coding into Enterprise Infrastructure with Arintra

Why We're Investing in Arintra

Today, we're proud to announce that Define Ventures is leading Arintra's $25M Series B with participation from the Yale New Haven Health (YNHH) Center for Health Care Innovation, and insiders Peak XV Partners, Endeavor Health Ventures, Y Combinator, and more. 

Arintra has built the first enterprise-grade autonomous coding platform designed for health systems. They work within every major care setting, across 23+ specialties (e.g. inpatient, general surgery, ambulatory, emergency department, hospitalist, radiology), across products including DRG validation, Clinical Documentation Improvement (CDI), denials, and appeals, and operate inside the EHR systems teams already use. Taken all together, Arintra’s autonomous coding platform covers 82% of professional billing volume.

Arintra already powers coding at leading health systems including Endeavor, Rochester, UC Davis, Mercy Medical, and Reid Health, is available in the Epic Toolbox and on the athenahealth Marketplace and, and received an A+ in Partnership from KLAS earlier this year. They are processing over $5B in claim value today across dozens of customers.

The Solution Set

Arintra reads a patient's chart straight out of the EHR and puts it through a system of 150+ specialized coding agents that work together, reasoning through the medical, operational, and billing context the way an expert coder would. Today, Arintra has been able to reach coding accuracy of 96% and 86% of claims are autonomously coded without human intervention, with the rest automatically sent to a human coder, with a clear paper trail showing exactly why each code was chosen.

‍What sets Arintra apart from narrow point solutions:

• First to span all major care settings. Arintra is the first autonomous coding platform built across the four care settings that matter to enterprise health systems: ambulatory, emergency, inpatient, and diagnostic care.

• The broadest specialty coverage. With 23+ specialties supported, Arintra can automate a far larger portion of a health system's coding activity through a single platform than narrowly focused competitors. Importantly, they are able to tackle some of the most complex specialties like inpatient and surgery.

• The first and only explainable audit trail embedded in the EHR. Arintra goes beyond generating a coding output; it gives health systems an explainable audit trail inside the EHR, so teams can understand, review, and defend every coding decision. 

• The only platform orchestrating professional coding across the enterprise. Because Arintra orchestrates coding across specialties and care settings within one platform, it has uniquely been able to build adjacent revenue-assurance products — CDI, DRG validation, and appeals and denials — on the same foundation.

‍The Challenge: Revenue Cycle Capacity Is Holding Health Systems Back‍

Health systems are under mounting financial pressure while the resources that keep revenue flowing, the physicians and certified coders, remain constrained. In order to stay financially resilient, health systems must now view medical coding as a strategic operational challenge instead of administrative overhead.

The numbers tell the story:

• Coder shortage. 66% of health information professionals reported staffing shortages in 2023, per AHIMA. AAPC estimates a 12% nationwide coding talent gap in 2025. The workforce isn't coming back. (AHIMA via BizForce | AAPC via Chiroko Health)
  
  
• Margin pressure. Kaufman Hall's adjusted year-to-date operating margin closed out 2025 at just 1.3%. Operating margins fell another 5% nationally through the first five months of 2026 versus a year earlier. Hospitals have no room left to absorb inefficiency. (Kaufman Hall | Becker's)
  
  
• Denials & leakage. Denials and appeals was the most pressing RCM challenge in 2026, with the average denied amount increasing by 14% in outpatient claims and 12% in inpatient claims - most shockingly, 90% of those denials are avoidable. (HFMA via Outsource Accelerator)

Legacy approaches can't close the gap: first generation autonomous coding tools still require human review of every chart because their dated technology stacks haven’t been able to break through specialities, care settings, and products in the way Artintra does today. Even newer point solutions automate only a single specialty, component of revenue cycle, or care setting, which leaves health systems to stitch together a patchwork of niche solutions while the bulk of their coding volume remains manual. The consequences are real: every human-coded chart risks delayed, inaccurate, or missed revenue;  every miscoded chart is a compliance risk; and every new service line adds cost that grows in lockstep with volume. Health systems need a way to grow without proportionally growing their revenue cycle:

"Health systems don't need another point solution. They need trustworthy infrastructure. Arintra is the first autonomous coding platform built for how enterprise health systems actually operate: every major care setting, the broadest specialty coverage, and an explainable audit trail inside the EHR. Arintra founders understand this need deeply, and their results speak for themselves, which is why we are excited to partner with them during this phase of growth.”

— Chirag Shah, Partner, Define Ventures

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Why Now and Why This Team?

Recent advances in AI have made autonomous coding technically possible, but the demand-side shift is just as important. Health systems facing sustained margin pressure are no longer piloting automation at the edges; they're beginning to adopt autonomous coding as enterprise infrastructure. Arintra sits at the convergence of that capability and that demand.

Arintra was founded by Nitesh Shroff, former research engineer at Zoox, and Preeti Bhargava, former data scientist at Demandbase, who both hold PhDs in artificial intelligence. Together, they're solving one of healthcare's largest operational bottlenecks, revenue cycle capacity, by bringing enterprise-grade autonomous medical coding to health systems. We have been incredibly impressed with Arintra’s operational discipline, technical acumen, and commercial momentum, which is why we are excited to partner with both Nitesh and Preeti as they build their revenue assurance vision for health systems. Their humility coupled with their commitment to delivering meaningful results time and time again with their enterprise customers gives us tremendous confidence in their ability to continue to scale Arintra.  

"Every inaccurately coded chart is money a health system earned and never collected. We built Arintra to close that gap at the source — transparently, auditably, and inside the systems teams already use. Coding has been our starting point, and we've already expanded into the broader revenue assurance infrastructure around it: what understands a chart well enough to code it understands enough to improve everything around it, upstream before a claim is sent and downstream when a payer pushes back. Define saw that nothing on the market matches the breadth and depth we've built, and we share a conviction that we can fundamentally change how health systems capture the revenue they've already earned."

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Looking Ahead

Autonomous revenue assurance across the enterprise means health systems can dedicate their resources to care, not paperwork. We couldn't be prouder to partner with Nitesh, Preeti and the Arintra team as they define the future of healthcare. 

To learn more about Arintra, please visit www.arintra.com.